Anticancer Drugs Oncology Pharmacology Physiotherapy Raloxifene


In this article we will discuss Raloxifene (Dosage Overview)

In this article, we will discuss Raloxifene (Dosage Overview). So, let’s get started.


Treatment and Prevention of Osteoporosis in Postmenopausal Women

Raloxifene is indicated for the treatment and prevention of osteoporosis in postmenopausal women.


Osteoporosis in Postmenopausal Women Indication
The recommended dosage is one 60 mg raloxifene tablet daily, which may be administered any time of day without regard to meals.

Recommendations for Calcium and Vitamin D Supplementation
For either osteoporosis treatment or prevention, supplemental calcium and/or vitamin D should be added to the diet if daily intake is inadequate. Postmenopausal women require an average of 1500 mg/day of elemental calcium. Total daily intake of calcium above 1500 mg has not demonstrated additional bone benefits while daily intake above 2000 mg has been associated with increased risk of adverse effects, including hypercalcemia and kidney stones. The recommended intake of vitamin D is 400-800 IU daily. Patients at increased risk for vitamin D insufficiency (e.g., over the age of 70 years, nursing home bound, or chronically ill) may need additional vitamin D supplements. Patients with gastrointestinal malabsorption syndromes may require higher doses of vitamin D supplementation and measurement of 25-hydroxyvitamin D should be considered.

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