Causes of Cor pulmonale

In this article, we will discuss about various Causes of Cor pulmonale. So, let’s get started.


Diseases of lung parenchyma

Chronic Obstructive Pulmonary Diseases such as emphysema and chronic bronchitis

Cystic fibrosis

Pulmonary fibrosis



Hypoventilation syndrome

Pulmonary vascular disease

Primary pulmonary hypertension

Thromboembolic pulmonary hypertension

Venoocclusive disease


Chest wall disorder


Neuromuscular disorders


Myasthenia gravis


Brittle Asthma

In this article, we will discuss about Brittle Asthma. So, let’s get started.

Brittle Asthma

Brittle asthma is a rare but severe form of asthma and is characterized by anarchic variation in the lung function despite appropriate treatment it is distinguished with other forms of asthma by severe recurrent attacks. There are two sub-types type 1 is characterized by sustained and chronic variability of PEFR (Peak expiratory flow rate) and type 2 is characterized by sudden unpredictable drops in PEFR while lung function test remains normal or near normal and symptoms also remains well controlled.

Type 1 is managed by oral steroids or infusion of beta2- agonists while type 2 is managed by allergen avoidance, subcutaneous adrenaline administration.

Patients with type 2 should wear MedicAlert bracelet for identification of the issue and should also carry epinephrine autoinjector.